A small study on the use of a heartburn medication, esomeprazole magnesium, was published today in the journalJAMA Internal Medicine.
A team of gastroenterologists, endocrinologists, and pharmacists have found that a drug known as omeprazole, which is sold as Nexium, is as effective as the well-known over-the-counter Z-pack medication, Prevacid. The drug has been shown to reduce symptoms of GERD, including acid reflux and GERD-like symptoms.
“Our team found that taking omeprazole increased GERD symptoms without affecting other esophageal symptoms, such as heartburn or acid regurgitation,” Dr. Charles H. W. Hirsch, a professor of medicine at the University of Maryland School of Medicine and the lead author of the study. “It is important to note that the treatment of GERD is generally considered a safe and effective option for many patients.”
The researchers reviewed a total of 5,664 participants who participated in the study between 2006 and 2020, with results from this study presented today at the annual meeting of the American Society for Gastroenterology.
The study compared the safety and efficacy of the omeprazole medication to a standard of care for GERD, Z-Pak, Zantac or other medications for acid reflux and GERD-like symptoms. The results suggest that omeprazole is as effective as Z-Pak and may be more effective than Z-Pack.
“We found that taking omeprazole increased GERD symptoms without affecting other esophageal symptoms, such as heartburn or acid regurgitation,” W. Hirsch, M. D., professor of medicine at the University of Maryland School of Medicine, said in a statement. “While the data did not provide evidence that PPIs are safe and effective for these patients, our findings suggest that taking omeprazole could be an effective treatment for GERD with a lower risk of heartburn.”
A new study was published inArchives of Internal Medicine, available at.
“The omeprazole medication is not as effective as Z-Pak as the Z-Pak, and the new study shows that PPIs and Z-Pack are similarly effective,” W. Hirsch said. “This is the first time that a drug known as omeprazole has been approved for the treatment of GERD without an increased risk of heartburn or other gastrointestinal symptoms. We were particularly interested in the use of PPIs in patients who are unable to tolerate Z-Pak or other medications for GERD.”
“We’re seeing many patients who may be more sensitive to acid, so it’s important to use PPIs when treating GERD with Z-Pak,” W. “Patients should discuss their acid-free condition with their doctor to determine whether they can take Z-Pak.”
The study was conducted by the University of Maryland School of Medicine and was published in
The study was published in the journal
“We also found that taking omeprazole did not alter the risk of gastric ulcers or bleeding associated with Z-Pak therapy, which is known to cause increased acid reflux and ulcers in the stomach.”
“Our findings are consistent with the results of other studies, including the results of our study showing that long-term use of PPIs for GERD, such as omeprazole, can increase the risk of gastric damage and bleeding, which could result in the occurrence of ulcers and bleeding in the stomach,” W. Hirsch continued.
The study also found that taking PPIs in patients who also have GERD can reduce symptoms of GERD, such as heartburn and acid regurgitation. The researchers suggest that patients who already have GERD should be started on a different acid-suppressing medication.
“Physicians should be aware that long-term use of PPIs for GERD can lead to an increased risk of cardiovascular and gastrointestinal events, such as heart attack,” W.
Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
You might be able to access information about our page on.You might be able to information about our page on.Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
Appeal from the US Food and Drug AdministrationThis product is available only in the form of capsules. You may receive a one-time use benefit from giving this product up for reflux disease or kidney disease. This medicine can be used regularly for reflux disease or kidney disease only if there are few erosions in the stomach. Esomeprazole Delayed-Release Capsules is a treatment for any symptoms of GERD, esophageal ulcers, stomach problems, heart disease, and other problems. It will not work for every kind of symptom. If the symptom does not improve after 7 days, call your doctor.
Appeal from the US FDANEXIUM is a medication used to treat certain types of heartburn. It contains the active ingredient esomeprazole magnesium, which belongs to a class of drugs called proton pump inhibitors (PPIs). Nexium is a prescription drug that can only be obtained with a valid prescription from a licensed healthcare professional. Nexium also treats conditions such as gastroesophageal reflux disease (GERD), ulcers caused by a too-late stomach acid, stomach ulcers caused by too much stomach acid, and peptic ulcers. It does not protect against sexually transmitted diseases like HIV, hepatitis B, and gonorrhea. Nexium is available in 20 milligrams (mg) tablets and 20 mg capsules. The retail price for Nexium 40 mg capsules is $12.25 for a supply of 14 capsules.
NEXIUM is used to treat reflux disease (GERD), a condition that affects the lining of the stomach. This condition can lead to symptoms such as heartburn, indigestion, and stomach upset. Nexium works by blocking the acid secretion from the stomach, thereby reducing the amount of stomach acid that is acid-producing. It is important to note that Nexium is not effective for GERD, and it does not prevent GERD from recurring. Nexium can cause stomach discomfort such as nausea, vomiting, and indigestion. In some cases, the symptoms of GERD may persist even after Nexium is discontinued. It is also important to note that Nexium does not cure GERD and is not indicated for prevention of GERD or GERD-related symptoms. Nexium can cause other side effects that may be bothersome to those with GERD and may require medical attention. It is important to note that the price of Nexium may vary depending on your location and your location. Always check your local or online pharmacy to ensure that you are purchasing a valid prescription for Nexium. If you have any questions about Nexium, contact your healthcare professional.
NEXIUMis a prescription drug that is used to treat heartburn (heartburn). Nexium is a proton pump inhibitor (PPI) that works by decreasing stomach acid production by blocking the production of stomach acid. It is available in 20 mg capsules and 40 mg capsules. Nexium is taken orally once a day, with or without food. It is important to follow your healthcare provider's instructions regarding the dosage and duration of treatment. Nexium is a proton pump inhibitor (PPI) that works by decreasing the amount of stomach acid produced by the stomach. Nexium is also used to treat conditions such as ulcers caused by too much stomach acid, ulcers caused by too much stomach acid, and Peptic Ulcers. Nexium is usually taken once a day with or without food, but it can be taken with or without food.
is a prescription drug that is used to treat reflux disease (GERD). Nexium works by decreasing the production of stomach acid, which is used to treat stomach acid reflux disease (a condition where stomach acid damages the esophagus). Nexium is available in 20 mg capsules and 40 mg capsules. Nexium is taken once a day, with or without food. Nexium is a proton pump inhibitor (PPI) that works by decreasing the production of stomach acid by blocking the production of stomach acids. Nexium is a proton pump inhibitor (PPI) that works by decreasing stomach acid production by blocking the action of stomach acid. Nexium is taken once a day, with or without food, but it can be taken with or without food.